ZONISAMIDE

Product Description

NAME :- ZONISAMIDE

IUPAC NAME :- benzo[d]isoxazol-3-ylmethanesulfonamide

CAS NO. :- 68291-97-4

FORMULA :- C8H8N2O3S

SYNONYMS :- ZON;ci-912;ad-810;pd110843;excegram;exceglan;Excegran; Zonegran;Excemide;ZONISAMIDE

APPLICATION :- For use as adjunctive treatment of partial seizures in adults with epilepsy.

DESCRIPTION :- Zonisamide is a sulfonamide anticonvulsant approved for use as an adjunctive therapy in adults with partial-onset seizures. Zonisamide may be a carbonic anhydrase inhibitor although this is not one of the primary mechanisms of action. Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels leading to a reduction of T-type calcium channel currents, or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of the inhibitory neurotransmitter GABA while enhancing the uptake of the excitatory neurotransmitter glutamate.