RAMIPRIL

Product Description

NAME :- RAMIPRIL

IUPAC NAME :- (2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[b]pyrrole-2-carboxylic acid

CAS NO. :- 87333-19-5

FORMULA :- C23H32N2O5

SYNONYMS :- 2S,3aS,6aS-1-(2S)-2- (1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclo-penta[b]pyrrole-2-carboxylic acid

APPLICATION :- An inhibitor of the angiotensin- coverting enzyme (ACE)

DESCRIPTION :- Ramipril is an inhibitor of the ACE (angiotensin- converting enzyme) that is reported to quickly hydrolyze into the active metabolite Ramiprilat. Studies indicate that Ramipril is a more potent inhibitor in comparison to Zofenopril (sc-208496). Acute coronary syndrome investigations demonstrate that Ramipril increases IL-10, and decreases the levels of MCP-1 and IL-18.