Pyrilamine maleate is an antihistamine medication that is commonly used to relieve symptoms associated with allergies, such as sneezing, itching, watery eyes, and runny nose.Pyrilamine maleate works by blocking the effects of histamine, a substance in the body that is released during an allergic reaction. By inhibiting histamine, pyrilamine maleate helps to alleviate allergy symptoms and provides temporary relief.