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PAMIDRONATE SODIUM
Product Details:
- Shelf Life 12 Months
- Solubility Water
- Storage Room Temperature
- Molecular Formula C3H9NNA2O7P2
- Medicine Name PAMIDRONATE SODIUM
- CAS No 57248-88-1
- Type Pharmaceutical Intermediates
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PAMIDRONATE SODIUM Price And Quantity
- 25 Kilograms
PAMIDRONATE SODIUM Product Specifications
- PAMIDRONATE SODIUM
- 99%
- Pharmaceutical Intermediates
- 57248-88-1
- Powder
- C3H9NNA2O7P2
- Room Temperature
- Water
- Medicine Grade
- 12 Months
PAMIDRONATE SODIUM Trade Information
- 500 Kilograms Per Day
- 1 Days
Product Description
NAME :- PAMIDRONATE SODIUM
IUPAC NAME :- disodium [3-amino-1-hydroxy-1-[hydroxy(oxido)phosphoryl]propyl]-hydroxyphosphinate
CAS NO. :- 57248-88-1
FORMULA :- C3H9NNA2O7P2
SYNONYMS :- ;pamidronate disodium;disodium (3-amino-1-hydroxypropane-1,1-diyl)bis[hydrogen (phosphonate)];pamidronate disodium salt;3-amino-1-hydroxy-1-phosphonopropyl phosphonic acid disodium salt;phosphonate, P,P'-(3-amino-1-hydroxypropylidene)bis-, sodium salt (1:2);
APPLICATION :- A farnesyl diphosphate synthase inhibitor
DESCRIPTION :- Pamidronate disodium salt is a bisphosphonate compound, which inhibits farnesyl diphosphate synthase and bone resorption. Studies suggest that Pamidronate disodium salt stimulates polymorphonuclear leukocyte and platelet derived nitric oxide production. It is believed that this nitric oxide production can lead to a negative feedback mechanism, which could restrict the inflammatory process and reduce bone resorption. Furthermore, bisphosphonates induce endothelial cell death, cancer cell apoptosis, and nuclear factor-B pathway activation, via the endothelial protein C receptor.
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