NAME :- ETORICOXIB
IUPAC NAME :- 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine
CAS NO. :- 202409-33-4
FORMULA :- C18H15CIN2O2S
SYNONYMS :- Algix;Etoxib;Etocox;MK 663;Tauxib;Etobrix;Arcoxia;Kingcox;MK 0663;Etropain
APPLICATION :- For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
DESCRIPTION :- Etoricoxib is a new selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme . This reduces the generation of prostaglandins (PGs) from arachidonic acid.